(Nasdaq: BIIB) today announced positive topline results from EVOLVE-MS-2, a large, randomized, double-blind, five-week, Phase 3 study of diroximel fumarate, an investigational, novel oral fumarate with a distinct chemical structure, for relapsing-remitting multiple sclerosis (RRMS), compared to TECFIDERA[R] (
dimethyl fumarate).
ENPNewswire-July 31, 2019--Alkermes plc - Diroximel Fumarate Demonstrated Significantly Improved Gastrointestinal Tolerability Profile Compared to
Dimethyl Fumarate in Patients with Multiple Sclerosis
Diroximel fumarate was statistically superior to
dimethyl fumarate on the study's pre-specified primary endpoint, with patients treated with diroximel fumarate self-reporting significantly fewer days of key gastrointestinal symptoms with intensity scores greater than or equal to2 on the Individual Gastrointestinal Symptom and Impact Scale, as compared to
dimethyl fumarate.
Police said Fabiosa sold
Dimethyl Trypticase, a party drug classified as a hallucinogen, worth P200,000 to an undercover agent in front of a hotel that led to the arrests.
A private company opened a chemical plant in Iran's Markazi province to produce ammonium hydroxide
dimethyl carbonate on February 3.
Summary: TEHRAN (FNA)- A private sector company opened a chemical plant in Markazi Province on Sunday to produce '
dimethyl carbonate ammonium hydroxide' for the first time in Iran.
Gaylord Chemical company, LLC is a manufacturer of
dimethyl sulfide and
dimethyl sulfoxide.
Reformulated skim milk with serum protein isolate contained higher concentrations of hydrogen sulfide, carbon disulfide,
dimethyl sulfide,
dimethyl disulfide,
dimethyl trisulfide and methional, compared to micellar casein concentrate-reformulated skim milk or skim milk after DSI or IND-UP.
Several widely used exempt VOCs include, but are not limited to, acetone, methyl acetate, t-butyl acetate (TBAC),
dimethyl carbonate, 2-amino-2-methyl-l-propanol (AMP), and parachlorobenzotrifluoride (PCBTF).
The degraded metabolites were similar to the control, except the absence of 1,3
dimethyl benzene and 4- phenyl but-3- ene- lyne.
However, to the best of our knowledge, no the first principle calculations of the full optimization of the five
dimethyl dodecahedranes, [C.sub.20][H.sub.18][(C[H.sub.3]).sub.2] derivatives using B3LYP/6-31G(d,p), have been reported.