episome

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Related to episomes: Plasmids

ep·i·some

 (ĕp′ĭ-sōm′)
n.
A segment of DNA in certain cells, especially bacterial cells, that can exist either autonomously in the cytoplasm or as part of a chromosome.

ep′i·so′mal adj.
ep·i·so′mal·ly adv.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

episome

(ˈɛpɪˌsəʊm)
n
(Microbiology) a unit of genetic material (DNA) in bacteria, such as a plasmid, that can either replicate independently or can be integrated into the host chromosome
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ep•i•some

(ˈɛp əˌsoʊm)

n.
a strand of DNA that is extrachromosomal, as a bacterial plasmid.
[< French épisome (1958); see epi-, -some3]
ep`i•so′mal, adj.
ep`i•so′mal•ly, adv.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.episome - DNA that is not incorporated into the genome but is replicated together with the genome (especially in bacterial cells)
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
épisome
References in periodicals archive ?
Considering the presence of high virus titer in the liver sample and the precedent of finding virus episomes in tissue for related parvoviruses (20), we used an inverse PCR-based approach to acquire the complete virus genome.
Also, on analysis of EBV DNA in the tumors, features akin to those found in PTLD including unique EBV DNA episomes (EBV small RNA, EBER, and EBV nuclear antigen2 (EBNA-2)) were noted.
In this context, EBV episomes tend to be absent in immunocompetent PCNSL patients, and other mechanisms of disease induction might be responsible for lymphomagenesis [43].
Using PCR (2 sets of specific primers), we did not detect the vector DNA either as episomes or anywhere in the iPSC genome analyzed, after about 10 passages.