Histoid leprosy was diagnosed when patients presented with papular and nodular lesions, confirmed by histopathology through the predominance of spindle-shaped cells and unusually large numbers of acid-fast bacilli.
Assessing the impact of phylogenetic incongruence on taxonomy, floral evolution, biogeographical
histoid and phylogenetic diversity.
Pseudotumor resulting from atypical mycobacterial infection: a "
histoid" variety of Mycobacterium avium-intracellulare complex infection.
'
Histoid leprosy', first described by wade, is an unusual variant of bacilliferous leprosy with classical clinical, histopathological and bacteriological findings with 3-6% incidence.
Of the 11 cases of leprosy, 7 cases (63.63%) were of lepromatous leprosy, 2 cases each were of
histoid leprosy, and tuberculoid leprosy.
Borderline tuberculoid leprosy was the most frequent morphologic type, seen in 56.3 per cent followed by borderlineborderline ( 1.5 per cent), borderline lepromatous ( 24.9 per cent), lepromatous leprosy ( 8.1 per cent), pure neuritic ( 8.1 per cent),
histoid and indeterminate leprosy ( 0.5 per cent each).
It also underlies the genesis of malakoplakia (139,140) (Figure 20, A and B),
histoid cutaneous infections caused by Mycobacterium leprae, (141) and florid lymphoid hyperplasia of the terminal ileum in patients infected with Yersinia.
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Concordance in case of indeterminate and
histoid leprosy were also included.
Histoid leprosy (HL) is a rare variant of multibacillary leprosy described by Wade, (1) clinically characterised by firm, reddish, or skin-coloured, shiny, dome-shaped or oval papules and nodules on normal appearing skin.
On the basis of the clinical findings, they were subdivided into subtypes of leprosy: BL leprosy, 29.03% (n = 18); BT leprosy, 27.14% (n = 17); TT leprosy, 17.24% (n = 11); and LL, 9.46% (n = 6), of which 3 cases were of
histoid leprosy, Mid-borderline leprosy, 6.45% (n = 4), and indeterminate leprosy, 5.08% (n = 3), were also found [Figure 1].
Abstract
Histoid leprosy is one of the rare kinds of lepromatous leprosy with specific clinical pathologic manifestations.