nephron

"Low-birth-weight children and those with loss of renal mass have a 'nephron deficit." It's believed that the remaining nephrons suffer from the glomerular hypertension that causes progressive injury and perpetuates the proteinuria even if there is no systemic hypertension.

Kidney tissue consists of numerous urinemaking units, known as nephrons, and urine-collecting tubules.

With indwelling Foley catheters, not only would untreated bladder infections be transferred into the kidneys, but also a kinked or plugged catheter would often result in buildup of intolerable pressures in the kidney's pelvis, thereby destroying many of the nephrons and glomeruli [filtering and excretory units].

Each one is made up of millions of tiny units called "nephrons" which filter the blood, removing toxic waste products, salts and water.

One result is a well-documented inverse association between birth weight and the number of nephrons a baby is born with, said Dr.

The kidneys remove urea from the blood through tiny filtering units called nephrons. Each nephron consists of a ball formed of small blood capillaries, called a glomerulus, and a small tube called a renal tubule.

In this small volume, they contain over a million nephrons. Blood is pumped through millions of capillary tubes which lead into the nephrons.

Preterm birth (before 37 weeks of pregnancy) interrupts kidney development and maturity during late-stage pregnancy, resulting in fewer nephrons forming (filters that remove waste and toxins from the body).

Lowering the toxic load protects nephrons and offers the potential to slow progression.

Central to the progression of CKD is the gradual and irreversible loss of nephrons, the individual functional units of the kidney.

van Velzen, "The effect of intrauterine growth retardation on the development of renal nephrons," British Journal of Obstetrics and Gynaecology, vol.