heme

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Related to heme: heme protein, Heme iron, Heme oxygenase

heme

(hēm)

A deep red, iron-containing compound, C₃₄H₃₂FeN₄O_4, that constitutes the nonprotein component of hemoglobin and certain other proteins.

[Short for hematin.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

heme

(him)

n.

an unstable, deep red, iron-containing blood pigment, C₃₄H₃₂N₄O₄Fe, obtained from hemoglobin.

[1920–25; shortening of hemoglobin]

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Noun

heme - a complex red organic pigment containing iron and other atoms to which oxygen binds

haem, haemitin, hematin, protoheme

pigment - dry coloring material (especially a powder to be mixed with a liquid to produce paint, etc.)

haemoglobin, Hb, hemoglobin - a hemoprotein composed of globin and heme that gives red blood cells their characteristic color; function primarily to transport oxygen from the lungs to the body tissues; "fish have simpler hemoglobin than mammals"

myoglobin - a hemoprotein that receives oxygen from hemoglobin and stores it in the tissues until needed

cytochrome - (biochemistry) a class of hemoprotein whose principal biological function is electron transfer (especially in cellular respiration)

References in periodicals archive ?

Disruption of an active site hydrogen bond converts human heme oxygenase-1 into a peroxidase.

Identification of genes for synthesis of the blue pigment, biliverdin IX[alpha], in the blue coral Heliopora coerulea

The antioxidative effect of whey proteins is mainly associated with beta-lactoglobulin and lactoferrin due to their ability to inactivate prooxidative heme proteins (ferrylmyoglobin) and to bind iron [14].

Effect of acid whey and freeze-dried cranberries on lipid oxidation and fatty acid composition of nitrite-/nitrate-free fermented sausage made from deer meat

In addition to generation of ROS from free Hb, iron released from heme degradation can result in the generation of additional ROS resulting in cellular damage.

Peptide Inhibitor of Complement C1 Inhibits the Peroxidase Activity of Hemoglobin and Myoglobin

These authors further showed that a defect in iron recycling accounts for dysregulation of iron homeostasis in human with heme oxygenase-1 deficiency [17].

Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice

The MPO light chain was not included in the alignment because it does not contain heme and the overall sequence similarity is even lower.

Hemoglobins Likely Function as Peroxidase in Blood Clam Tegillarca granosa Hemocytes

Mishra, "The heme oxygenase system suppresses perirenal visceral adiposity, abates renal inflammation and ameliorates diabetic nephropathy in Zucker diabetic fatty rats," PLoS One, vol.

Insulin Resistance, Type 1 and Type 2 Diabetes, and Related Complications 2017

However, he adds, cooking in water "would not necessarily remove the carcinogenic potential of, for example, heme iron."

Red meat and colorectal cancer: exploring the potential HCA connection

Under the company's Molecular Oncology and Cellular Tumor Marker permit, the HEME FISH-based assays was awarded approval for detection of amplifications or rearrangements of DNA in several hematologic cancers, including leukemias, lymphomas and myelomas in order to form a diagnosis and/or to evaluate prognosis or remission of disease.

Rosetta Genomics awarded conditional approval for the HEME FISH-based assays in New York State

Heme oxygenase-1 immunostaining was weakly present in tubules of both SHAM and RP groups (Fig.