isotypic

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i·so·type

(ī′sə-tīp′)

1. A biological specimen or other element that is a duplicate of the holotype.

2. Any of several classes or subclasses of immunoglobulins, such as immunoglobulins A and G, that are distinguished by differences in the amino acid sequence of the constant regions of their heavy chains. All isotypes are usually found in every individual of a species.

i′so·typ′ic (-tĭp′ĭk) adj.

i′so·ty′py (-tī′pē) n.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

isotypic

(ˌaɪsəʊˈtɪpɪk)

adj

(Geological Science) mineralogy having a similar or identical crystal structure, and, optionally, also having analogous chemical formulae

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

References in periodicals archive ?

The control for FITC- or PE-coupled antibodies was isotypic mouse IgG1.

The Hypoxia-Mimetic Agent Cobalt Chloride Differently Affects Human Mesenchymal Stem Cells in Their Chondrogenic Potential

50 [micro]l EMP suspension was incubated with 3 [micro]l of anti-human CD31-FITC (557508, BD, USA) or 3 [micro]l of isotypic immunoglobulins IgG1-FITC (551954, BD, USA).

AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway

Both structures are isotypic with very related geometric parameters.

Crystal Structure and Cyclic Voltammetric Studies on the Metal Complexes of N-(Dimethylcarbamothioyl)-4-fluorobenzamide

Mouse monoclonal antiactive [beta]-catenin (ABC) which is specific against nuclear [beta]-catenin, and goat anti-mouse IgG-rhodamine were obtained from Millipore (Massachusetts, USA), whereas rabbit polyclonal anti-cleaved caspase-3 antibody was from Calbiochem (Massachusetts, USA), EMD Chemicals, goat anti-rabbit IgG-FITC, rabbit anti-goat IgGHRP conjugated and IgG1 mouse isotypic control were from Vector Laboratories (Peterborough, UK).

Exogenous secreted frizzled-related protein-4 modulates steroidogenesis of rat granulosa cells through Wnt/[beta]-catenin and PI3K/AKT signaling pathways

FACopyrightrey, Different Adsorption Behaviors of Methane and Carbon Dioxide in the Isotypic Nanoporous Metal Terephthalates MIL-53 and MIL-47, J.

Adsorption and Separation Capabilities of Short Linear Alkanes in Two MOFs with Different Topology

Cells were washed twice by phosphate buffered solution (PBS) and then incubated with either isotypic control or monoclonal antibodies against PE-CD45, FITC-CD71, FITC-CD117, APC-CD115, and APC-RANKL (receptor activator of nuclear factor [kappa]B ligand) for 30 min on ice in the dark, respectively.

Panax notoginseng saponins suppress radiation-induced osteoporosis by regulating bone formation and resorption

This is not the case of planar systems; on the contrary, it simplifies the analysis because of the reduction to isotypic components.

Limit cycles for a class of quintic [Z.sub.6]-equivariant systems without infinite critical points

Results were expressed as the percentage difference compared with isotypic control (IC) using the formula [mean fluorescence intensity (MFI) of sample-MFI of IC]/MFI of IC.

Decreased expression of the aryl hydrocarbon receptor in ocular Behcet's disease

Fluorescence labeled liposomes were prepared with anti-EGFR antibodies or isotypic human immunoglobulins coupled with the DSPE-PEG2000Mal linker.

Targeted antiepidermal growth factor receptor (Cetuximab) immunoliposomes enhance cellular uptake in vitro and exhibit increased accumulation in an intracranial model of glioblastoma multiforme

Isotypic controls were also used in all experiments, including mouse IgG1 (679.1Mc7) and IgG2a (UCTH-1) labeled with FITC and PE, respectively.

Cytokine pattern of T lymphocytes in acute Schistosomiasis mansoni patients following treated praziquantel therapy

The isotypic space U(r,[mu]) inherits the action of [G.sub.r] and therefore decomposes as