Casabiell et al., "Synthesis of
leptin in human placenta," Endocrinology, vol.
The present study aimed to investigate umbilical cord (UC)
leptin receptor (LEPR) levels in PE and to examine the direct effect of
leptin on IL-8 production by human endometrial endothelial cells (HEECs) and human umbilical vein endothelial cells (HUVECs), thus to describe the function of
leptin in PE.
Researchers know that
leptin, a hormone produced by fat cells, is important in the control of body weight both in humans and mice.
"We didn't know how a high-fat diet or overeating leads to
leptin resistance," Fukuda said.
Blocking the interaction of GIP with the brain restores
leptin's ability to inhibit appetite and results in weight loss in mice.
In reaction to rapid weight loss, the brain seems to go into 'starvation' mode, reducing
leptin levels so your appetite is stimulated, encouraging you to eat more and get fatter.
To the best of my knowledge, this is the first study that fully describes seven polymorphic sites of bubaline
leptin gene in Anatolian water buffaloes.
Leptin is a novel and promising molecule in research that may link body weight (BW), body mass index (BMI), and neurodegenerative diseases (5, 6).
In view of intense hyperphagia followed by rapid weight gain, early age of onset, family history of EOO and low level of circulating
leptin, a diagnosis of monogenic obesity due to LEP gene mutation was considered.
The serum concentration of
leptin determines the energy status of the body in adipose tissue.
Kisspeptin and
Leptin levels were measured by enzyme linked immune sorbent assay before down regulation of ovaries and initiation of treatment protocol of ART.Failure of procedure was detected by beta human chorionic gonadotropin 25mIU/ml and cardiac activity on trans-vaginal scan were declared pregnant.
Tomoe Hirota, from Osaka City University in Japan, and colleagues investigated the association between fasting
leptin levels and sleep quality in 182 patients with type 2 diabetes.