placebo


Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.

pla·ce·bo

 (plə-sē′bō)
n. pl. pla·ce·bos or pla·ce·boes
1.
a. A substance that has positive effects as a result of a patient's perception that it is beneficial rather than as a result of a causative ingredient.
b. An inactive substance or preparation used as a control in an experiment or test to determine the effectiveness of a medicinal drug.
2. Something of no intrinsic remedial value that is used to appease or reassure another.
3. (plä-chā′bō) Roman Catholic Church The service or office of vespers for the dead.

[Latin placēbō, I shall please, first person sing. future tense of Latin placēre, to please; see plāk- in Indo-European roots. Sense 3, from Late Latin placēbō, I shall please, the first word of the first antiphon of the vespers service (taken from a phrase in the following psalm, placēbō Dominō in regiōne vīvōrum, "I shall please the Lord in the land of the living").]
Word History: Like the word dirge, placebo has its origin in the Office of the Dead, the cycle of prayers traditionally sung or recited for the repose of the souls of the dead. The traditional liturgical language of the Roman Catholic Church is Latin, and in Latin, the first word of the first antiphon of the vespers service is placēbō, "I shall please." This word is taken from a phrase in the psalm text that is recited after the antiphon, placēbō Dominō in regiōne vīvōrum, "I shall please the Lord in the land of the living." The vespers service of the Office of the Dead came to be called placebo in Middle English, and the expression sing placebo came to mean "to flatter, be obsequious." Chaucer, for example, uses the phrase on two occasions. In the Summoner's Tale, a friar offers the following piece of advice: Beth war, therfor, with lordes how ye pleye. / Singeth placebo and 'I shal if I kan,' "Be wary, therefore, how you deal with lords. / Sing 'Placebo' and 'I shall if I can.'" Placebo eventually came to mean "flatterer" and "sycophant." In the 1700s, placebo began to be used of prescriptions written by a physician solely to please a patient, as by satisfying the patient's desire to take medicine. In many cases, the patient would actually benefit, thanks to what became known as the placebo effect. Later, placebo came to refer to neutral substances used in controlled studies testing the effectiveness of medications.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

placebo

(pləˈsiːbəʊ)
n, pl -bos or -boes
1. (Medicine) med an inactive substance or other sham form of therapy administered to a patient usually to compare its effects with those of a real drug or treatment, but sometimes for the psychological benefit to the patient through his believing he is receiving treatment. See also control group, placebo effect
2. something said or done to please or humour another
3. (Roman Catholic Church) RC Church a traditional name for the vespers of the office for the dead
[C13 (in the ecclesiastical sense): from Latin Placebo Domino I shall please the Lord (from the opening of the office for the dead); C19 (in the medical sense)]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pla•ce•bo

(pləˈsi boʊ for 1; plɑˈtʃeɪ boʊ for 2)

n., pl. -bos, -boes.
1.
a. a substance having no pharmacological effect but given to placate a patient who supposes it to be a medicine.
b. a pharmacologically inactive substance or a sham procedure administered as a control in testing the efficacy of a drug or course of action.
2. the vespers for the office of the dead.
[1175–1225; Middle English < Latin placēbō I shall be pleasing, acceptable]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

pla·ce·bo

(plə-sē′bō)
A substance resembling a drug but containing only inactive ingredients, used especially in scientific experiments to test the effectiveness of a drug. Researchers give one group of people a real drug and another group a placebo and then determine whether the people taking the drug get better results than the people taking the placebo.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.placebo - an innocuous or inert medication; given as a pacifier or to the control group in experiments on the efficacy of a drug
active placebo - a placebo used in experimental tests of a drug that has noticeable side effects; "an active placebo mimics the side effects of the experimental drug"
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
2.placebo - (Roman Catholic Church) vespers of the office for the dead
vesper - a late afternoon or evening worship service
Church of Rome, Roman Catholic Church, Roman Church, Western Church, Roman Catholic - the Christian Church based in the Vatican and presided over by a pope and an episcopal hierarchy
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
lumelääkeplasebo

placebo

[pləˈsiːbəʊ]
A. N (placebos or placeboes (pl)) → placebo m
B. CPD placebo effect Nefecto m placebo
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

placebo

[pləˈsiːbəʊ] nplacebo mplacebo effect neffet m placeboplace card nmarque-place mplace mat nset m de table
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

placebo

n (Med) → Placebo nt
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

placebo

[pləˈsiːbəʊ] nplacebo m inv
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

pla·ce·bo

n. placebo, sustancia anodina sin valor medicinal gen. usada en experimentos comparativos;
___ controlled trialprueba de control ___.
English-Spanish Medical Dictionary © Farlex 2012

placebo

n (pl -bos o -boes) placebo
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in classic literature ?
The chant is called the Placebo from the first word.
A king, when he presides in counsel, let him beware how he opens his own inclination too much, in that which he propoundeth; for else counsellors will but take the wind of him, and instead of giving free counsel, sing him a song of placebo.
In psychology, a placebo works by two explanations.
They have found that 'under the right circumstances, a placebo can be just as effective as traditional treatments.'
Papp Clinical Research and Probity Medical Research in Peterborough, Ontario, Canada, and colleagues randomly assigned 267 patients to receive a TYK2 inhibitor, BMS-986165, orally (3 mg every other day, 3 mg daily, 3 mg twice daily, 6 mg twice daily, or 12 mg daily) or placebo.
After giving a brief overview over current evidence and models on the development of placebo hypoalgesia and nocebo hyperalgesia including conditioning and expectation approaches, we will turn to studies that stress the significance of conditioning and demonstrate that conditioning effects might have been misunderstood and/or underestimated.
It turns out placebos work even when patients know they are taking a dummy pill.
The word placebo brings with it connotations of deception, fakery, and ineffectiveness.
The inception of RCT dates back to World War II when in an effort to impose an objective and scientific discipline onto the extraordinary postwar expansion of medical research, the components of the double-blind RCT were adopted and coalesced together for the first time.1 These included blind assessment (usually meaning a placebo control), random assignment to comparable groups, and inferential statistics as a surrogate for determinism.2
They were randomized into treatment groups who were given either magnesium oxide 800 mg or 1,200 mg daily or placebo. Treatment lasted a total of eight weeks.
A major interest was shown in identifying the factors that play a role in the placebo phenomenon.