FRAMESHIFT

Noun Verb Adjective

Definition

FRAMESHIFT of, pertaining to, or causing a type of mutation consisting of the insertion or deletion of one or more nucleotides in the nucleic acid structure of a gene, when the number of base pairs inserted or deleted is not a multiple of three. If the addition or deletion occurs in multiples of three, the unaffected nucleotides in the genome remain in the proper order ("frame") to be correctly translated into protein; in such cases of insertions or deletions not causing a frame shift, a functional though altered protein may be produced by the organism. Frameshift mutations cause more profound changes in the composition of the protein resulting from translation of the mutated gene.

Word Analysis

Usage and Context

The word FRAMESHIFT can be used in various contexts in written and spoken English. As a valid Scrabble word, it represents a legitimate part of the English lexicon, even if it may not be commonly used in everyday conversation.

Learning Tip

Understanding words like FRAMESHIFT helps expand your vocabulary and appreciation for the diversity of the English language. Many words in the Scrabble dictionary come from specialized fields, historical periods, or other languages, showing how English continues to evolve and incorporate new terms.

Scrabble Information

Word: FRAMESHIFT

Length: 10 letters

Dictionary: Valid in TWL and SOWPODS

Status: Official Scrabble word

Usage

The word FRAMESHIFT can be used in various contexts. As a valid Scrabble word, it can be played on the Scrabble board according to standard game rules.