GALL

bold and impudent behaviour

the contents of the gall bladder; bile (proverbial for its bitterness).

annoyance or resentment

a sore on the skin made by chafing

make (someone) feel annoyed or resentful

make sore by rubbing

an abnormal growth formed in response to the presence of insect larvae, mites, or fungi on plants and trees, especially oaks