There were no major qualitative differences in polyphenol content between AHS and PEHS; therefore, the precipitation pro-cedures used to remove other soluble material did not result in selective losses in benefit (Fig.
Table 1 Relevant analytical data for components isolated in AHS and PEHS (sec also Fig.
However, the relative activity of PEHS was much higher and evident even at concentrations <10 [micro]g/ml.
This process, termed pseudoepitheliomatous hyperplasia (PEH; or pseudocarcinomatous hyperplasia), is potentially associated with organoid nevi, nonhealing ulcers, chronic dermatitides, reactions to underlying neoplasms, and selected infections of the skin.
PEH in Chronic Dermatitides.--Pseudoepitheliomatous hyperplasia is a potentially prominent finding in a variety of chronic dermatitides.
PEH Associated With Underlying Neoplasms.--When it represents a reaction to subjacent neoplasms, epidermal PEH is principally seen in conjunction with granular cell tumor, dermatofibroma, xanthogranuloma, dermatofibrosarcoma protuberans, or melanocytic proliferations, such as Spitz nevus and spindle cell nevus of Reed (21-26) (Figure 2, A and B).